Medical News

August 25, 2004 — Noni , has been extensively used in folk medicine by Polynesians for over 2,000 years. Noni is a traditional food and medicine in many tropical areas including the Pacific Islands, Southeast Asia, India, and the Philippines. Ethnobotanical data is plentiful on the uses of the fruit, leaves, and root of the plant. Ancient Hawaiians used noni fruit for both internal and topical applications.

Noni is still used by the local population in Hawaii for sugar control diseases, high vascular pressure, heart health maintenance, abnormal growths, and other chronic disorders, although no controlled clinical studies exist to support these uses. Based on clinical practice and animal studies, a polysaccharide-rich substance from noni fruit juice attacks abnormal cells in several different ways.

Noni fruit juice seems to act indirectly against abnormal growths, primarily through immunostimulatory effects. Animal studies found that adding 10% noni fruit juice to drinking water for one week significantly reduced DNA adduct formation in rodents. DNA adducts change the shape of DNA and initiate the formation of abnormal cells (i.e. chemicals in cigarette smoke are known to cause DNA adducts thereby initiating lung abnormal growths in smokers).

A low dosage of noni juice (6-15mg daily for 4-5 days) reduced the formation of DNA adducts by 30% in the heart, 41% in the lung, 42% in the liver, and 80% in the kidney of female rats. Even more dramatic reductions were obtained in male mice: 60% in the heart, 50% in the lung, 70% in the liver, and 90% in the kidney.

Noni juice also has potent antioxidant activity. Researchers conclude that noni juice could be used in clinical applications as a supplemental agent to reduce side-effects and improve chemotherapy. In animal studies, noni juice treatments prolonged the life span of mice by more than 75%.

Noni fruit contains: The active ingredients are polysaccharides found in a polysaccharide-rich substance in the water-soluble fraction of the fruit juice. A novel trisaccharide fatty acid ester was recently identified from the fruits of noni. The fruit also contains the plant acids, hexoic acid and octoic acid, and paraffin.

The potassium concentration in noni juice samples was determined and found to be 56.3 mEq/L. Other ubiquitous substances are also found in the fruit. Several noni products are marketed with the information that the key active ingredients in noni are alkaloids called proxeroxine and proeronase. These compounds have yet to be identified by conventional researchers and have not been reported in peer-reviewed scientific publications; it appears that the claims may be false.

Noni juice, as a rich source of potassium, is contraindicated in cases of chronic renal insufficiency. There is a case report on noni juice involving a man with chronic renal insufficiency that self-medicated with noni juice and presented to a clinic with hyperkalemia despite claiming adherence to a low-potassium diet.

The potassium concentration in noni juice samples was determined and found to be 56.3 mEq/L, similar to that in orange juice and tomato juice.In other regions, the Noni is eaten raw with salt (Indochina, Australian Aborigines); or cooked as a curry. Noni may also be fed to pig livestock. The young leaves can also be eaten as a vegetable and contain protein (4-6%).

Noni seeds may be roasted and eaten. As you can see Noni is used in many ways and some may even surprise you. Noni juice doses ranges from 1 ounce (or 2 tablespoons) per day for the maintenance level in healthy individuals, to up to 12 ounces per day for those suffering from serious degenerative conditions.

It is suggested that individuals work up to the higher dosages slowly, starting with the maintenance dosage of 1 ounce daily, followed by two daily dosages of 1 ounce and so on until the higher dosages are taken several times per day. At the higher dosages, it is recommended to be under the supervision of a qualified medical practitioner familiar with the properties of noni juice.

Noni contains nutritional enzymes, anthraquinones and polysaccharides, all known to have various health benefits. Noni is the common Polynesian name for Noni Juiice also Known as Indian Mulberry. The plant indigenous to India, Malaysia, and Southeast Asia, is a Noni of evergreen ranging in size from a small bush to a tree 20 or 30 feet high.

Approximately the size of a potato the Noni fruit has a lumpy appearance and a waxy, semi-translucent skin that ranges in color as it ripens from green to yellow to almost white. Native recognize it sight unseen because of the fruit’s rancid smell when fully ripe. This smell decreases some as the fruit is fermented and the juice is prepared. The taste is also improved during this processing.

Noni plant are used to contain fever and as a tonic (Chinese, Japan, Polynesia); leaves, flowers, fruit, bark to treat eye problems, skin wounds and abscesses, gum and throat problems, respiratory ailments, constipation, fever (Pacific Islands, Polynesia); to treat stomach pains and after child birth (Marshall Islands).

Heated leaves applied to the chest relieve coughs, nausea, colic (Malaysia); juice of the leaves is taken for arthritis (Philippines). The Noni fruit is taken for lumbago, asthma and dysentery (Indochina); pounded unripe fruit is mixed with salt and applied to cuts and broken bones; ripe fruit is used to draw out pus from an infected boil (Tahiti & Polynesia).

Juices of over-ripe fruits are taken to regulate menstrual flow, ease urinary problems (Malay); fruits are used to make a shampoo (Malay, Polynesian) and to treat head lice (Tahiti & Polynesia). Other exotic diseases treated with the plant include diabetes and venereal diseases.

Noni as a medicine: the fruit and its juices have been used in the treatment of diabetes, heart troubles and high blood pressure, with different portions prescribed for different illnesses. The prepared juices can be diluted with clean water or fruit juices, and drunk before meals and at resting periods. Treatment is always best during more relaxed times.

Noni is believed to have been brought here centuries ago by early Polynesian settlers, and is a native of the Pacific Islands, Asia, Australia and even South America. It is also recommended to take noni juice on an empty stomach for maximum benefits (or one half hour before meals) – and it is also recommended to drink a glass of water following the dosage to potentiate the benefits.

Noni fruit is picked at its yellow stage and placed in jars. The jars are place in a sunny spot, letting it set there for five days to a week or more, until the fruit turns to mush and sun-charged juices drain into the bottom of the jar. It is these juices that are strained into a smaller jar, and then refrigerated until used.

This method is not very practical as you would have to have a tree around all the time and it is by far the most unpleasant way to use the Noni fruit.The young Noni unripe fruit can be pounded thoroughly with salt and the mixture placed carefully on deep cuts and on broken bones. Sometimes the juice is squeezed out of this mixture, boiled and applied to the wounds.

It is good to seek the advice of a health practitioner before using any supplements. The ripe fruit can be used as a poultice for facial blemishes, rubbed until the oil disappears, and also to draw out the pus and core from an infected sore or boil, such as with a staph infection. In the old days, this was tied on with a bandage of tapa bark cloth. The dressing of Noni could be reapplied more than once for difficult cases.

Noni is receiving more and more attention from modern herbalists, medical physicians, and high-tech biochemists. Scientific studies within the last few decades lend support to the Polynesians’ claims of its unusual healing power. Some of the health-related ingredients of Noni fruit that have been isolated are Morindone, Morindine, Acubin, Terpene compounds, L. Asperuloside, various Anthraquinones, Alazarin, Caproic Acid, Caprylic Acid, Scopoletin, Damnacanthal, and Alkaloids.

Alkaloids are colorless, complex, bitter organic bases, and they are essential to maintaining healthy stasis in the body. Dr. Ralph Heinicke, a respected biochemist formerly at the University of Hawaii, has dedicated himself to the study of one alkaloid in particular found in Noni called xeronine.

Even though the Noni fruit has only negligible amounts of xeronine, the juice does contain very large amounts of a precursor to the essential alkaloid called proxeronine. Proxeronine is a colloid that, unlike most colloids, contains neither sugars, amino acids, nor nucleic acids and thereby has been overlooked by most biochemists.

This compound initiates the release of xeronine in the intestinal tract after it comes in contact with a specific enzyme which is also contained in the Noni juice.The body produces xeronine in order to activate enzymes and to regulate and give structure to proteins. According to Dr. Heinicke, without xeronine life would not exist. However extracting xeronine from the human body has been impossible to date.

The body’s protein molecules consume the alkaloid immediately after it is created; and therefore, there is never an appreciable, insoluble amount in the body.

August 25, 2004 — Noni , has been extensively used in folk medicine by Polynesians for over 2,000 years. Noni is a traditional food and medicine in many tropical areas including the Pacific Islands, Southeast Asia, India, and the Philippines. Ethnobotanical data is plentiful on the uses of the fruit, leaves, and root of the plant. Ancient Hawaiians used noni fruit for both internal and topical applications.

Noni is still used by the local population in Hawaii for sugar control diseases, high vascular pressure, heart health maintenance, abnormal growths, and other chronic disorders, although no controlled clinical studies exist to support these uses. Based on clinical practice and animal studies, a polysaccharide-rich substance from noni fruit juice attacks abnormal cells in several different ways.

Noni fruit juice seems to act indirectly against abnormal growths, primarily through immunostimulatory effects. Animal studies found that adding 10% noni fruit juice to drinking water for one week significantly reduced DNA adduct formation in rodents. DNA adducts change the shape of DNA and initiate the formation of abnormal cells (i.e. chemicals in cigarette smoke are known to cause DNA adducts thereby initiating lung abnormal growths in smokers).

A low dosage of noni juice (6-15mg daily for 4-5 days) reduced the formation of DNA adducts by 30% in the heart, 41% in the lung, 42% in the liver, and 80% in the kidney of female rats. Even more dramatic reductions were obtained in male mice: 60% in the heart, 50% in the lung, 70% in the liver, and 90% in the kidney.

Noni juice also has potent antioxidant activity. Researchers conclude that noni juice could be used in clinical applications as a supplemental agent to reduce side-effects and improve chemotherapy. In animal studies, noni juice treatments prolonged the life span of mice by more than 75%.

Noni fruit contains: The active ingredients are polysaccharides found in a polysaccharide-rich substance in the water-soluble fraction of the fruit juice. A novel trisaccharide fatty acid ester was recently identified from the fruits of noni. The fruit also contains the plant acids, hexoic acid and octoic acid, and paraffin.

The potassium concentration in noni juice samples was determined and found to be 56.3 mEq/L. Other ubiquitous substances are also found in the fruit. Several noni products are marketed with the information that the key active ingredients in noni are alkaloids called proxeroxine and proeronase. These compounds have yet to be identified by conventional researchers and have not been reported in peer-reviewed scientific publications; it appears that the claims may be false.

Noni juice, as a rich source of potassium, is contraindicated in cases of chronic renal insufficiency. There is a case report on noni juice involving a man with chronic renal insufficiency that self-medicated with noni juice and presented to a clinic with hyperkalemia despite claiming adherence to a low-potassium diet.

The potassium concentration in noni juice samples was determined and found to be 56.3 mEq/L, similar to that in orange juice and tomato juice.In other regions, the Noni is eaten raw with salt (Indochina, Australian Aborigines); or cooked as a curry. Noni may also be fed to pig livestock. The young leaves can also be eaten as a vegetable and contain protein (4-6%).

Noni seeds may be roasted and eaten. As you can see Noni is used in many ways and some may even surprise you. Noni juice doses ranges from 1 ounce (or 2 tablespoons) per day for the maintenance level in healthy individuals, to up to 12 ounces per day for those suffering from serious degenerative conditions.

It is suggested that individuals work up to the higher dosages slowly, starting with the maintenance dosage of 1 ounce daily, followed by two daily dosages of 1 ounce and so on until the higher dosages are taken several times per day. At the higher dosages, it is recommended to be under the supervision of a qualified medical practitioner familiar with the properties of noni juice.

Noni contains nutritional enzymes, anthraquinones and polysaccharides, all known to have various health benefits. Noni is the common Polynesian name for Noni Juiice also Known as Indian Mulberry. The plant indigenous to India, Malaysia, and Southeast Asia, is a Noni of evergreen ranging in size from a small bush to a tree 20 or 30 feet high.

Approximately the size of a potato the Noni fruit has a lumpy appearance and a waxy, semi-translucent skin that ranges in color as it ripens from green to yellow to almost white. Native recognize it sight unseen because of the fruit’s rancid smell when fully ripe. This smell decreases some as the fruit is fermented and the juice is prepared. The taste is also improved during this processing.

Noni plant are used to contain fever and as a tonic (Chinese, Japan, Polynesia); leaves, flowers, fruit, bark to treat eye problems, skin wounds and abscesses, gum and throat problems, respiratory ailments, constipation, fever (Pacific Islands, Polynesia); to treat stomach pains and after child birth (Marshall Islands).

Heated leaves applied to the chest relieve coughs, nausea, colic (Malaysia); juice of the leaves is taken for arthritis (Philippines). The Noni fruit is taken for lumbago, asthma and dysentery (Indochina); pounded unripe fruit is mixed with salt and applied to cuts and broken bones; ripe fruit is used to draw out pus from an infected boil (Tahiti & Polynesia).

Juices of over-ripe fruits are taken to regulate menstrual flow, ease urinary problems (Malay); fruits are used to make a shampoo (Malay, Polynesian) and to treat head lice (Tahiti & Polynesia). Other exotic diseases treated with the plant include diabetes and venereal diseases.

Noni as a medicine: the fruit and its juices have been used in the treatment of diabetes, heart troubles and high blood pressure, with different portions prescribed for different illnesses. The prepared juices can be diluted with clean water or fruit juices, and drunk before meals and at resting periods. Treatment is always best during more relaxed times.

Noni is believed to have been brought here centuries ago by early Polynesian settlers, and is a native of the Pacific Islands, Asia, Australia and even South America. It is also recommended to take noni juice on an empty stomach for maximum benefits (or one half hour before meals) – and it is also recommended to drink a glass of water following the dosage to potentiate the benefits.

Noni fruit is picked at its yellow stage and placed in jars. The jars are place in a sunny spot, letting it set there for five days to a week or more, until the fruit turns to mush and sun-charged juices drain into the bottom of the jar. It is these juices that are strained into a smaller jar, and then refrigerated until used.

This method is not very practical as you would have to have a tree around all the time and it is by far the most unpleasant way to use the Noni fruit.The young Noni unripe fruit can be pounded thoroughly with salt and the mixture placed carefully on deep cuts and on broken bones. Sometimes the juice is squeezed out of this mixture, boiled and applied to the wounds.

It is good to seek the advice of a health practitioner before using any supplements. The ripe fruit can be used as a poultice for facial blemishes, rubbed until the oil disappears, and also to draw out the pus and core from an infected sore or boil, such as with a staph infection. In the old days, this was tied on with a bandage of tapa bark cloth. The dressing of Noni could be reapplied more than once for difficult cases.

Noni is receiving more and more attention from modern herbalists, medical physicians, and high-tech biochemists. Scientific studies within the last few decades lend support to the Polynesians’ claims of its unusual healing power. Some of the health-related ingredients of Noni fruit that have been isolated are Morindone, Morindine, Acubin, Terpene compounds, L. Asperuloside, various Anthraquinones, Alazarin, Caproic Acid, Caprylic Acid, Scopoletin, Damnacanthal, and Alkaloids.

Alkaloids are colorless, complex, bitter organic bases, and they are essential to maintaining healthy stasis in the body. Dr. Ralph Heinicke, a respected biochemist formerly at the University of Hawaii, has dedicated himself to the study of one alkaloid in particular found in Noni called xeronine.

Even though the Noni fruit has only negligible amounts of xeronine, the juice does contain very large amounts of a precursor to the essential alkaloid called proxeronine. Proxeronine is a colloid that, unlike most colloids, contains neither sugars, amino acids, nor nucleic acids and thereby has been overlooked by most biochemists.

This compound initiates the release of xeronine in the intestinal tract after it comes in contact with a specific enzyme which is also contained in the Noni juice.The body produces xeronine in order to activate enzymes and to regulate and give structure to proteins. According to Dr. Heinicke, without xeronine life would not exist. However extracting xeronine from the human body has been impossible to date.

The body’s protein molecules consume the alkaloid immediately after it is created; and therefore, there is never an appreciable, insoluble amount in the body.